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A luxurious serum with the SYN-AKE peptide and rose water
A silky and completely non-greasy serum for mature skin that needs hydration and a softer, more relaxed look. The SYN-AKE peptide, inspired by a snake peptide, helps smooth expression lines , while Damask rose water with oat and argan oil moisturises and nourishes your skin. We make it in our own production in the EU.
5.0 out of 526 ratings
SYN-AKEpeptide for expression lines
30 mlnon-greasy serum
EUour own production
Who it's for
For mature skin, including skin prone to imperfections
You have mature skin and want it to look smoother, firmer and more rested.
You like a light, non-greasy texturethat also works well under make-up.
Your skin is prone to imperfections and needs its moisture and sebum balanced.
Do not use on irritated skin or if you are sensitive to any of the ingredients. Not suitable for children.
Do you have sensitive skin? First try the serum on a small area, for example your forearm, and wait 24 to 48 hours.
Benefits
What it does for your skin
The SYN-AKE peptide helps smooth expression lines and your skin looks more relaxed.
It supports the production of elastin and collagen, tightening and rejuvenating your skin.
It helps balance moisture and sebum levels and restore a healthy skin barrier.
It hydrates and leaves your skin soft, supple and nourished.
It is absolutely non-greasy and silky; it absorbs and leaves no film.
Your skin looks fresher, more rested and brighter.
It is applied under your cream and enhances its effect.
Natural oils, rose hydrosol and active ingredients are rich in minerals, vitamins and fatty acids, giving your skin a luxurious feel.
Key ingredients: SYN-AKE peptide, Damask rose water, oat and argan oil
SYN-AKE peptide
Dipeptide Diaminobutyroyl Benzylamide Diacetate
a neuropeptide developed after the structure of the Temple Viper snake peptide
relaxes micro-contractions of the muscles, helping to smooth expression lines
helps prevent them from deepening
a vegan form; no snake was harmed
Damask rose water
Rosa Damascena Flower Water
organic rose hydrosol
moisturises the skin and gives it a pleasant scent
smooths and firms, harmonises the skin
wonderful for mature and sensitive skin
Oat lipid oil
Avena Sativa Kernel Oil
a high concentration of ceramides
omega-3 and omega-6 fatty acids
long-lasting hydration
skin is soft, elastic and nourished
Argan oil
Argania Spinosa Oil
an organic oil rich in vitamin E and fatty acids
strongly regenerating and softening
restores vitality even to mature skin
Squalane
Squalane
a natural moisturising ingredient that locks water into the skin
strengthens the natural lipid barrier
prevents excessive water evaporation
smooths, softens and restores your skin's radiance
Other active ingredients
BoswelliaBoswellia Serrata Resin ExtractViaPure Boswellia for anti-ageing care: it soothes and firms the skin, slows down elastase and improves the skin's barrier function.
ResveratrolResveratrolA polyphenol that plants use to protect themselves from pests and moulds; some scientists nickname it the elixir of youth.
Echium oil and beta-NMNEchium Plantagineum Seed, Nicotinamide MononucleotideEchium oil is wonderful for dry skin and helps smooth fine lines; NMN plays a role in energy production in the cells.
Pentylene glycolPentylene GlycolHydrates without drying, binds water and helps deliver active ingredients deeper into the skin, which then looks brighter.
Essential oilsBoswellia Carterii Gum Oil, Helichrysum Italicum Flower Oil, Tanacetum Annuum Flower Oil, Citrus JunosFrankincense soothes and renews the skin, Italian everlasting rejuvenates, blue tansy soothes, and yuzu brightens and tones.
Siligel and lysolecithinXanthan Gum, Sclerotium Gum, Pullulan, Lecithin, LysolecithinA natural gelling agent gives the serum its silky texture; lysolecithin increases the skin's hydrophilicity.
How to use
Three steps, morning and evening
1Morning and evening, gently cleanse and pat your skin dry.
2Apply a thin layer of serum and gently massage it in.
3Pat it into your face and neck, let it absorb and follow with your cream.
What to expect
What you will feel after the first use
After applyingThe serum spreads well and sinks into the skin. Your skin doesn't stay greasy and you can hardly feel the serum on it.
During the dayYour skin is supple and pleasantly nourished. Customers wear it under make-up too.
With regular useTogether with the toner and cream, it forms a routine you'll love coming back to. Every skin is different.
“Si krásna is a truly luxurious serum. Just like the cream, it spreads well and my skin doesn't stay greasy. … Together with the cream it makes a super duo.”
Who's behind it
Family business, our own production in the EU
I wanted a serum that feels silky on the skin and not greasy at all, yet carries the SYN-AKE peptide, rose water and oils from oats and argan. Under Si krásna cream, morning and evening.
ErikaErika Bundalovádeveloper & co-founder of Panakeia
Together with Erika: Albi (marketing), Martina (help with choosing) and Patrik (tinctures).
Storage: at room temperature, away from heat sources and direct sunlight
Caution: For external use only. Avoid contact with eyes and mucous membranes. Do not use on irritated or sensitive skin or if you are sensitive to any of the ingredients. Not suitable for children. Keep out of the reach of children.
Responsible person: PANAKEIA SK s.r.o., Žabinská 2, 911 05 Trenčín
Questions
What you ask most often
What is SYN-AKE?
A peptide (Dipeptide Diaminobutyroyl Benzylamide Diacetate) developed after the structure of the Temple Viper snake peptide. It relaxes micro-contractions of the muscles and so helps smooth expression lines. It is vegan; no snake was harmed.
Is the serum greasy?
No. It is absolutely non-greasy and silky, even though it contains oils. Customers write that it absorbs straight away, they can hardly feel it on their face, and it works under make-up too.
How do I combine it with a cream?
Apply the serum first, let it absorb and then use your cream. The serum delivers the active ingredients, the cream seals them in. According to reviews, Si krásna serum and cream make a super duo for our customers.
Can I use it morning and evening?
Yes, morning and evening on clean skin. Some customers wear it in the morning and reach for Kopaničiarska žehlička in the evening.
Is it suitable for the eye area too?
One customer also uses it around her eyes and writes that it doesn't sting. But don't apply it into the eyes and avoid contact with mucous membranes.
What skin is it suitable for?
For all skin types, especially mature skin, including skin prone to imperfections, that needs hydration and renewal. If your skin is sensitive, do a patch test on a small area first.
What does a patch test look like?
Apply a small amount to a small area, for example your forearm or behind your ear, and wait 24 to 48 hours. If no redness, itching or swelling appears, you can use the serum.
How long does 30 ml last?
With daily use, roughly two to three months. The small size is handy for travelling too.
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4,9
The average product rating is 4,9 out of 5 stars.29 ratings
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List of ratings
3Customer
The product rating is 3 out of 5 stars.
06/09/2026
- Nepríjemná vôňa
- Pomalé vstrebávanie
5Customer
The product rating is 5 out of 5 stars.
03/08/2026
Super krém a sérum ❤️
5Customer
The product rating is 5 out of 5 stars.
06/05/2026
Serum Si krasna,tak ako aj krem som si kupila uz viackrat.Je dobre roztieratelne,nemasti plet,nestipu ma po nom oci,kedze ja velmi nemam rada ocne kremy,pouzivam ho aj na ocne okolie.Tiez nema silnu vonu a skvelo sa doplna spolu s kremom Si krasna.Vrelo odporucam,urcite nesklame.
5Customer
The product rating is 5 out of 5 stars.
08/12/2025
Šermu sa krásne vstrekne do pokožky zatiaľ používam krátko
5Customer
The product rating is 5 out of 5 stars.
18/10/2025
- Ziadna
S liftingovym serom Si krasna som velmi spokojna.Mam ho uz druhykrat.Je jemne,nemastí pokozku,tiez ho na tvari ani necitite,ma nevtieravu vonu,velmi dobre sa rozotiera.Pokozka zostane jemna a spolu s pletovou vodou alebo tonikom a kremom,vytvori velmi dobry efekt.Je dolezite pravidelne pouzivanie a aj pravidelne cistenie tvare .Za mna spolu s kremom TOP produkt.
5Customer
The product rating is 5 out of 5 stars.
09/09/2025
Si krasna,je naozaj luxusne serum.Tak ako kremik,sa tiez dobre roztiera,neostava plet mastna.Pouzivam ho rano,pretoze na noc si davam serum Kopaniciarsku zehlicku,ktore je tiez vynikajuce,pozivala som ho predtym rano aj vecer.Splna vsetky moje ocakavania,citim sa velmi pohodlne,lebo ma pocas dna plet nesvrbi od suchosti,nemusim mysliet na to,ze sa musim pocas dna znovu natriet.Som velmi spokojna,nelutujem,ze som si kupila prave toto serum.Tiez vhodne svojim balenim aj na cestovanie.Spolu s kremikom tvoria super duo.Zlozenie je tiez kvalitne,za mna urcite odporucam vyskusat.
5Customer
The product rating is 5 out of 5 stars.
05/08/2025
Skvelé sérum, som s ním veľmi spokojná. Asi najviac z produktov, ktoré som vyskúšala.
4Customer
The product rating is 4 out of 5 stars.
23/07/2025
Nevidela som na svojej pleti žiadnu pozitívnu zmenu pri používaní tohto sera a to som nakúpila viac produktov Panakeia ako mi bolo odporučené a dodržala som proces od čistenia až po sérum....
5Customer
The product rating is 5 out of 5 stars.
30/06/2025
Jemnejšia pleť, dobrý pocit.
5Customer
The product rating is 5 out of 5 stars.
28/06/2025
Luxus v tejto ampulke. Uz z názvu je jasne čo po používaní môžeme cakat. Serum je nemastne, vhodne aj pod makeup. U mna velka spokojnosť.
5Customer
The product rating is 5 out of 5 stars.
21/06/2025
+ Zatiaľ ešte som to použila asi 2x takže celkom hodnotiť neviem ,ale pleť je hladsia a menej mastná,len by som uvítala formulku koľko krát do týždňa môžem používať sérum,alebo masku
5Customer
The product rating is 5 out of 5 stars.
26/11/2024
+ So sérom som spokojná, vyhovuje mojej pleti.
5Customer
The product rating is 5 out of 5 stars.
22/03/2024
Ľahko sa nanáša a rýchlo vpije do pokožky.
5Customer
The product rating is 5 out of 5 stars.
25/07/2023
+ Kvalita
5Customer
The product rating is 5 out of 5 stars.
18/04/2023
+ Ak by bolo v ponuke litrove balenie, nevaham a kupujem
5Customer
The product rating is 5 out of 5 stars.
04/04/2023
+ Používam pravidelne, a som veľmi spokojná.
5Customer
The product rating is 5 out of 5 stars.
11/01/2023
+ Vyborne hydratuje, vypina, rychlo sa vstrebava
5Customer
The product rating is 5 out of 5 stars.
29/11/2022
+ Zdá sa mi že pleť je hladšia, nepôsobí mdlym dojmom
5Customer
The product rating is 5 out of 5 stars.
14/05/2022
+ Pleť mám krásne sviežu, hebkú a vláčnu.Vhodné na suchú pleť.Určite si ho ešte objednám.Len odporúčam
- Žiadne
Sérum je skvelé,omladzuje a zvláčňuje pokožku. Ja mám suchú zrelú pleť, u mňa veľká spokojnosť Cena zodpovedá kvalite
5Customer
The product rating is 5 out of 5 stars.
01/01/1970
zatial maximálna spokojnosť, sérum sa pekne vpije do pokožky a tá je potom taká príjemne akurátna, vyživená (mám suchú pokožku)